Publications

58. G. Fumagalli, S. Stanton and J. F. Bower*; Recent methodologies that exploit C-C single bond cleavage of strained ring systems by transition metal complexes. Chem. Rev. 2017, In press. Invited contribution to the 2017 thematic issue on C-H and C-C functionalisation.

57. N. J. Race, A. Faulkner, G. Fumagalli, T. Yamauchi, J. S. Scott, M. Rydén-Landergren, H. A. Sparkes and J. F. Bower*; Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters. Chem. Sci. 2017, In press. (open access)56. G.-W. Wang, N. G. McCreanor, M. H. Shaw, W. G. Whittingham and J. F. Bower*; New initiation modes for directed carbonylative C-C bond activation: rhodium-catalyzed (3+1+2) cycloadditions of aminomethylcyclopropanes. J. Am. Chem. Soc. 2016, 138, 13501-13504. (open access)

55. G. A. M. Jardim, J. F. Bower* and E. N. da Silva Júnior*; Rh-catalyzed reactions of 1,4-benzoquinones with electrophiles: C-H iodination, bromination and phenylselenation. Org. Lett. 2016, 18, 4454-4457.

publication 55

54.  N. G. McCreanor, S. Stanton and J. F. Bower*; Capture-collapse heterocyclization: 1,3-diazepanes by C-N reductive elimination from rhodacyclopentanones. J. Am. Chem. Soc. 2016, 138, 11465-11468. (open access)

publication 54

53. M. H. Shaw and J. F. Bower*; Synthesis and applications of rhodacyclopentanones derived from C-C bond activation. Chem. Commun. 2016, 52, 10817-10829 (open access review article)

Publication 53

52. I. R. Hazelden, X. Ma, T. Langer and J. F. Bower*; Diverse N-heterocyclic ring systems via aza-Heck cyclizations of N-(pentafluorobenzoyloxy)sulfonamides. Angew. Chem. 2016, 128, 11364-11368; Angew. Chem. Int. Ed. 2016, 55, 11198-11202. (open access)

Publication 52

51. G. E. M. Crisenza, E. Dauncey and J. F. Bower*; C2-Alkenylation of N-heteroaromatic compounds via Brønsted acid catalysis. Org. Biomol. Chem. 2016, 14, 5820-5825. Invited contribution to the 2016 New Talent Special Issue. (open access)

Publication 51

50. A. S. Henderson, J. F. Bower* and M. C. Galan*; Carbohydrates as enantioinduction components in stereoselective catalysis. Org. Biomol. Chem. 2016, 14, 4008-4017. (open access review article)

Publication 50

49. G. A. M. Jardim, E. N. da Silva Júnior* and J. F. Bower*; Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives. Chem. Sci. 2016, 7, 3780-3784. (open access)Publication 49

48. G. E. M. Crisenza and J. F. Bower*; Branch selective Murai-type alkene hydroarylation reactions. Chem. Lett. 2016, 45, 2-9. (open access review article)

Publication 48

47. N. J. Race, A. Faulkner, M. H. Shaw and J. F. Bower*; Dichotomous mechanistic behavior in Narasaka-Heck cyclizations: electron rich Pd-catalysts generate iminyl radicals. Chem. Sci. 2016, 7, 1508-1513. (open access)

Publication 48

46. M. H. Shaw, W. G. Whittingham and J. F. Bower*; Directed carbonylative (3+1+2) cycloadditions of amino-substituted cyclopropanes and alkynes: reaction development and increased efficiencies using a cationic rhodium system. Tetrahedron 2016, 72, Symposium-in-print, Catalytic C–C bond formation by C–H functionalization and C–C bond cleavage, 2731-2741. (open access)

publication 44

45. G. E. M. Crisenza, O. O. Sokolova and J. F. Bower*; Branch selective alkene hydroarylation by cooperative destabilization: iridium-catalyzed ortho-alkylation of acetanilides. Angew. Chem. 2015, 127, 15079-15083; Angew. Chem. Int. Ed. 2015, 54, 14866-14870. (open access)

Publication 46

44. A. S. Henderson, S. Medina, J. F. Bower* and M. C. Galan*; Nucleophilic aromatic substitution as an approach to challenging carbohydrate-aryl ethers. Org. Lett. 2015, 17, 4846-4849. (open access)

43. M. H. Shaw, R. A. Croft, W. G. Whittingham and J. F. Bower*; Modular access to substituted azocanes via a rhodium-catalyzed cycloaddition-fragmentation strategy. J. Am. Chem. Soc. 2015, 137, 8054-8057. (open access)

publication 43

42. A. Faulkner, J. S. Scott and J. F. Bower*; An umpolung approach to alkene carboamination: palladium catalyzed 1,2-amino-acylation, -carboxylation, ‑arylation, -vinylation and -alkynylation. J. Am. Chem. Soc. 2015, 137, 7224-7230. (open access)

publication 42

41. S. Medina, A. S. Henderson, J. F. Bower and M. C. Galan*; Stereoselective synthesis of glycosides using (salen)Co catalysts as promoters. Chem. Commun. 2015, 51, 8939-8941. (open access)publication 41

40. N. J. Race and J. F. Bower*; Synthesis of heteroaromatic compounds by alkene and enyne metathesis. Top. Heterocycl. Chem. DOI: 10.1007/7081_2015_145. (review article)

39. M. H. Shaw, N. G. McCreanor, W. G. Whittingham and J. F. Bower*; Reversible C-C bond activation enables stereocontrol in Rh-catalyzed carbonylative cycloadditions of aminocyclopropanes. J. Am. Chem. Soc. 2015, 137, 463-468. (open access)

Publication 39

38. A. S. Henderson, J. F. Bower* and M. C. Galan*; Carbohydrate-based N-heterocyclic carbenes for enantioselective catalysis. Org. Biomol. Chem. 2014, 12, 9180-9183. (open access)

publication 38

37. G. E. M. Crisenza, N. G. McCreanor and J. F. Bower*; Branch selective iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy. J. Am. Chem. Soc. 2014, 136, 10258-10261. (open access)

Publication 37

36. A. Faulkner, N. J. Race, J. S. Scott and J. F. Bower*; Copper catalyzed Heck-like cyclizations of oxime esters. Chem. Sci. 2014, 5, 2416-2421. (open access)

Publication 36

35.  N. J. Race and J. F. Bower*; Palladium catalyzed cyclizations of oxime esters with 1,2-disubstituted alkenes: synthesis of dihydropyrroles. Org. Lett. 2013, 15, 4616-4619. (open access)

Publication 35

34.  M. H. Shaw, E. Y. Melikhova, D. P. Kloer, W. G. Whittingham and J. F. Bower*; Directing group enhanced carbonylative ring expansions of amino-substituted cyclopropanes: rhodium catalyzed multicomponent synthesis of N-heterobicyclic enones. J. Am. Chem. Soc. 2013, 135, 4992-4995. (open access)

Publication 34

33.  P. M. Murray,* J. F. Bower, D. K. Cox, E. K. Galbraith, J. S. Parker and J. B. Sweeney*; A robust first-pass protocol for the Heck-Mizoroki reaction. Org. Process Res. Dev. 2013, 17, 397-405.

32.  A. Faulkner, J. S. Scott and J. F. Bower*; Palladium catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes: synthesis of α,α-disubstituted dihydropyrroles and studies towards an asymmetric protocol. Chem. Commun. 201349, 1521-1523. (open access)

publication 32

31.  A. Faulkner and J. F. Bower*; Highly efficient Narasaka-Heck cyclizations mediated by P(3,5-(CF3)2C6H3)3: facile access to N-heterobicyclic scaffolds. Angew. Chem. 2012, 124, 1707-1711; Angew. Chem. Int. Ed. 2012, 51, 1675-1679.

Link to full-size graphical abstract

30.  T. J. Donohoe,* J. F. Bower and L. K. M. Chan; Olefin cross-metathesis for the synthesis of heteroaromatic compounds. Org. Biomol. Chem. 2012, 10, 1322-1328.

        • Highlighted as a “Hot” Emerging Area.

29.  T. J. Donohoe,* J. F. Bower, D. B. Baker, J. A. Basutto, L. K. M. Chan and P. Gallagher; Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence. Chem. Commun. 2011, 47, 10611-10613.

28.  T. J. Donohoe,* J. A. Basutto, J. F. Bower and A. Rathi; Heteroaromatic synthesis via olefin cross-metathesis: entry to polysubstituted pyridines. Org. Lett. 2011, 13, 1036-1039.

27.  J. F. Bower and M. J. Krische*; Formation of C-C bonds via iridium catalyzed hydrogenation and transfer hydrogenation. Top. Organomet. Chem. 2011, 34, 107-138.

26.  T. J. Donohoe,* J. F. Bower and J. A. Basutto; Olefin cross-metathesis based approaches to furans: procedures for the preparation of di- and trisubstituted variants. Nature Protocols 2010, 5, 2005-2010.

25.  T. J. Donohoe,* N. J. Race, J. F. Bower and C. K. A. Callens; Substituted pyrroles via olefin cross-metathesisOrg. Lett. 2010, 12, 4094-4097.

24.  T. J. Donohoe* and J. F. Bower; An expedient route to substituted furans via olefin cross-metathesis. Proc. Natl. Acad. Sci. U.S.A. 2010,107, 3373-3376.

23.  J. F. Bower,* J. Rujirawanich and T. Gallagher*; N-Heterocycle construction via cyclic sulfamidates. Applications in synthesis. Org. Biomol. Chem. 2010, 8, 1505-1519.

22.  T. J. Donohoe,* J. F. Bower, J. A. Basutto, L. P. Fishlock, P. A. Procopiou and C. K. A. Callens; Ring-closing metathesis for the synthesis of heteroaromatics: evaluating routes to pyridines and pyridazines. Tetrahedron 2009, 65, Symposium-in-print, Modern applications of transition metal catalysis in heterocycle synthesis, 8969-8980.

21.  T. J. Donohoe,* L. P. Fishlock, J. A. Basutto, J. F. Bower, P. A. Procopiou and A. L. Thompson; Synthesis of substituted pyridines and pyridazines via ring closing metathesis. Chem. Commun. 2009, 3008-3010.

20.  J. F. Bower and M. J. Krische*; Hydrogenation for C-C bond formation. In Handbook of Green Chemistry – Green Catalysis, Volume 1: Homogeneous Catalysis. P. T. Anastas and R. H. Crabtree (Eds.), Wiley-VCH: Weinheim, 2009, 205-254.

19.  J. F. Bower, I. S. Kim, R. L. Patman and M. J. Krische*; Catalytic carbonyl addition through transfer hydrogenation: a departure from preformed organometallic reagents. Angew. Chem. 2009121, 36-48; Angew. Chem. Int. Ed. 2009, 48, 34-46.

18.  R. L. Patman, J. F. Bower, I. S. Kim and M. J. Krische*; Formation of C-C bonds via catalytic hydrogenation and transfer hydrogenation: vinylation, allylation and enolate addition of carbonyl compounds and imines. Aldrichimica Acta 2008, 41, 95-104.

17.  J. S. Parker,* J. F. Bower, P. M. Murray, B. Patel and P. Talavera; Kepner-Tregoe decision analysis as a tool to aid route selection. Part 3. Application to a back-up series of compounds in the PDK project. Org. Process Res. Dev. 2008, 12, 1060-1077.

16.  F. Shibahara, J. F. Bower and M. J. Krische*; Diene hydroacylation from the alcohol or aldehyde oxidation level via ruthenium-catalyzed C-C bond-forming transfer hydrogenation: synthesis of β,γ-unsaturated ketones. J. Am. Chem. Soc. 2008, 130, 14120-14122.        

15.  R. L. Patman, V. M. Williams, J. F. Bower and M. J. Krische*; Carbonyl propargylation from the alcohol or aldehyde oxidation level employing 1,3-enynes as surrogates to preformed allenyl metal reagents: a ruthenium catalyzed C-C bond forming transfer hydrogenation. Angew. Chem. 2008, 120, 5298-5301; Angew. Chem. Int. Ed. 2008, 47, 5220-5223.

14.  F. Shibahara, J. F. Bower and M. J. Krische*; Ruthenium catalyzed C-C bond forming transfer hydrogenation: carbonyl allylation from the alcohol or aldehyde oxidation level employing acyclic 1,3-dienes as surrogates to preformed allyl metal reagents. J. Am. Chem. Soc. 2008, 130, 6338-6339.

13.  J. F. Bower, R. L. Patman and M. J. Krische*; Iridium catalyzed C-C coupling via transfer hydrogenation: carbonyl addition from the alcohol or aldehyde oxidation level employing 1,3-cyclohexadiene. Org. Lett. 200810, 1033-1035.

        • Highlighted in SYNFACTS 2008, 505.

12.  J. F. Bower, E. Skucas, R. L. Patman and M. J. Krische*; Catalytic C-C coupling via transfer hydrogenation: reverse prenylation, crotylation and allylation from the alcohol or aldehyde oxidation level. J. Am. Chem. Soc. 2007, 129, 15134-15135.

        • Highlighted in SYNFACTS 2008, 293.

11.  E. Skucas, J. F. Bower and M. J. Krische*; Carbonyl allylation in the absence of preformed allyl metal reagents: reverse prenylation via iridium catalysed hydrogenative coupling of dimethylallene. J. Am. Chem. Soc. 2007, 129, 12678-12679.

10.  J. F. Bower, P. Szeto and T. Gallagher*; Cyclic sulfamidates as precursors to alkylidene pyrrolidines and piperidines. Org. Lett. 2007, 9, 4909-4912.

9.  J. F. Bower, P. Szeto and T. Gallagher*; Enantiopure 1,4-benzoxazines via 1,2-cyclic sulfamidates.  Synthesis of levofloxacin. Org. Lett. 2007, 9, 3283-3286.

8.  J. F. Bower, A. J. Williams, H. Woodward, P. Szeto, R. M. Lawrence and T. Gallagher*; Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of α-phosphono lactams. Org. Biomol. Chem. 2007, 5, 2636-2644.

7.  J. F. Bower, T. Riis-Johannessen, P. Szeto, A. J. Whitehead and T. Gallagher*; Stereospecific construction of substituted piperidines.  Synthesis of (-)-paroxetine and (+)-laccarin. Chem. Commun. 2007,728-730.

        • Highlighted in SYNFACTS 2007, 574.

6.  J. F. Bower, P. Szeto and T. Gallagher*; Cyclic sulfamidates as versatile lactam precursors.  An evaluation of synthetic strategies towards (-)-aphanorphine. Org. Biomol. Chem. 2007, 5, 143-150.

5.  J. F. Bower, S. Chakthong, J. Švenda, A. J. Williams, R. M. Lawrence, P. Szeto and T. Gallagher*; Reactivity of cyclic sulfamidates towards sulfur-stabilised enolates. Stereocontrolled synthesis of functionalised lactams. Org. Biomol. Chem. 2006, 4, 1868-1877.

4.  J. F. Bower, P. Szeto and T. Gallagher*; Cyclic sulfamidates as lactam precursors. An efficient asymmetric synthesis of (-)-aphanorphine. Chem. Commun. 2005, 5793-5795.

3.  J. F. Bower, J. Švenda, A. J. Williams, J. P. H. Charmant, R. M. Lawrence, P. Szeto and T. Gallagher*; Cyclic sulfamidates as vehicles for the synthesis of substituted lactams. Org. Lett. 2004, 6, 4727-4730.

2.  J. F. Bower, S. A. Cotton,* J. Fawcett, R. S. Hughes and D. R. Russell; Praseodymium complexes of 2,2′-bipyridine; the crystal and molecular structures of Pr(bipy)3(NCS)3, Pr(bipy)2(NO3)3, Pr(bipy)2Cl3(OH2)·EtOH and Pr(bipy)(S2CNEt2)3. Polyhedron 2003, 22, 347-354.

1.  J. F. Bower, S. A. Cotton,* J. Fawcett* and D. R. Russell; Bis(2,2′-bipyridyl-N,N‘)tris(nitrato-O,O‘)neodymium. Acta Cryst. 2000, C56, e8-e9.